Single layer

Single layer of various shapes and sizes are the most common type of tablets and represent the majority of the tablets produced. Even though it looks simple to formulate, many conflicting factors needs to be taken into account to ensure robust formulation as well as high production output. While lubricant is commonly used to reduce the ejection forces, over-lubrication might have an impact on your dissolution.

MEDELPHARM Science Lab can help you in:

• APIs & Excipients characterization
• Formulation design and development
• Tableting DoE implementation
• Key production process parameters optimization
• Feasibility assessment of external lubrication versus internal lubrication Feasibility assessment of dry granulation
• Feasibility assessment of dry granulation

Those are few examples that our Science Lab can offer. We are always ready for new challenges. Get in touch with us to learn how we can help!

Preventing APIs incompatibility or providing multiple release profiles in the same formulation are some of the reasons formulators look at developing multi-layers. Such development requires specialized tablet presses and a deep understanding of multi-layer challenges, leading to a time-consuming and complex project.

MEDELPHARM Science Lab can help you in:

• The characterization of the different layers to design a robust multi-layer formulation
• Testing your bi-layer or even tri-layer formulation with small amount of product at a speed equivalent to the one in production
• Evaluation of critical process parameters such as tamping force which is critical to get good adhesion between layers
• Production of small batches for analytical method development, early stability or prototypes for your marketing

Those are few examples that our Science Lab can offer. We are always ready for new challenges. Get in touch with us to learn how we can help!

Tab-in-tab also known as dry coating or compression coated tablets are composed of two parts: the inner core and the dry surrounding shell. One of the applications is to combine different API release rates in the same tablet. The outer shell sould release

MEDELPHARM Science Lab can help you in:

• Production of the core for tab-in-tab
• Testing your tab-in-tab formulation with a small amount of product at a speed equivalent to the one in production
• Evaluation of critical process parameters such as core centering which may have an impact on dissolution profile
• Production of small batches for analytical method development, early stability or prototypes for your marketing

Those are few examples that our Science Lab can offer. We are always ready for new challenges. Get in touch with us to learn how we can help!

Mini-tablets represent a new trend in solid dosage form design that offers advantages such as dose flexibility and combined various release kinetics. Mini-tablets are patient-friendly systems for pediatric and geriatric people as they are easy to swallow with diameter smaller than 3 mm. Designing a mini-tablet formulation can be challenging as it requires specialized technology, tooling and expertise.

MEDELPHARM Science Lab can help you in:

• Characterization of your formulation using mono-tip punches thanks to our innovative dual scale force measurement system
• Rapid screening of formulations
• Evaluation of critical process parameters
• Production of homogeneous small batches using multi-tips tooling and our new innovative force feed shoe

Those are few examples that our Science Lab can offer. We are always ready for new challenges. Get in touch with us to learn how we can help!

Core rods tablets are very complex shaped tablets that are typically used by the catalyst or nuclear industry. The inclusion of holes in a tablet increases the surface area. Developing such tablets can be challenging at lab scale as it requires specific technology, tooling and expertise.

MEDELPHARM Science Lab can help you in:

• Quickly producing core rods tablets thanks to the STYL’One Evo and specific tooling
• Testing different tooling in no time
• Production of prototypes or small batches

Those are few examples that our Science Lab can offer. We are always ready for new challenges. Get in touch with us to learn how we can help!

One example of LCT is multilayer osmotic pump formulation. It can be configured to contain several drug layers containing either different drugs or drug concentration.

MEDELPHARM Science Lab can help you in:

• Producing LCT with up to five layers and three products
• Evaluation of critical process parameters of a multi-layer tablet
• Production of small batches that could be send for laser drilling

Those are few examples that our Science Lab can offer. We are always ready for new challenges. Get in touch with us to learn how we can help!